SERPINA7 Antikörper (AA 168-302)

Produktnummer ABIN1724893

Dieser Maus Monoklonal Antikörper erkennt spezifisch SERPINA7 in ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für SERPINA7 Antikörper (AA 168-302) (ABIN1724893)

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SERPINA7 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 1C3H11

Produktdetails anti-SERPINA7 Antikörper

Bindungsspezifität: AA 168-302

Verwendungszweck: SERPINA7 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human SERPINA7 (AA: 168-302) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-SERPINA7 Antikörper (ABIN1724893)

Yan, Yan, Ou: "Human thyroxine binding globulin (TBG) promoter directs efficient and sustaining transgene expression in liver-specific pattern." in: Gene, Vol. 506, Issue 2, pp. 289-94, (2012) (PubMed).

Duhan, Patston: "Explanation for the high heat stability of thyroxine binding globulin-Chicago." in: Endocrine regulations, Vol. 44, Issue 2, pp. 43-7, (2010) (PubMed).

Details zu SERPINA7

Target: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Andere Bezeichnung: SERPINA7

Hintergrund: There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Molekulargewicht: 46.3 kDa

UniProt: P05543

Pathways: Hormone Transport